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AstraZeneca, a worker packages the company's Evusheld medication.Highlights Long-acting antibody combination has been granted the EUA in the US for COVID-19 prevention AstraZeneca has initiated engagements with Indian authorities to provide evidence of evusheld Company said studies are underway to provide information on impact of Omicron variant on Evusheld
Biopharmaceutical multinational AstraZeneca on Thursday said it has initiated engagements with Indian health authorities to provide the latest evidence of Evusheld, its COVID-19 prevention drug for people with weakened immune system which has received emergency use authorisation (EUA) in the US.
The long-acting antibody combination has been granted the EUA in the US for COVID-19 prevention in adults and adolescents (above 12 years and weighing 40kg or more) with moderate to severely weakened immune system who may not have an adequate immune response to COVID-19 vaccination, as well as those individuals for whom COVID-19 vaccination is not recommended, the company said.
"We welcome this news and the opportunity it provides to support the unmet needs of high risk and immune-compromised patients and we have already initiated engagements with the relevant health authorities in India to provide them with the latest evidence," AstraZeneca India Pharma Ltd Managing Director Gagandeep Singh Bedi said in a statement.
Stating that the Food and Drug Administration's EUA approval for Evusheld is an important milestone globally, he said, "Recent data from the Phase III PROVENT trial showed a robust efficacy profile and AZD7442 (Evusheld) has so far demonstrated protection of up to six months against COVID-19 in this population."
"In India, the company intends to submit its application after emergency use authorisation by USFDA with a hope that addition of this monoclonal antibody cocktail will provide adequate ammunition in fight against COVID-19 disease especially for high risk vulnerable and immunocompromised patients," AstraZeneca said.
About 2 per cent of the global population is considered at increased risk of an inadequate response to a COVID-19 vaccine, it added.
"In India, this percentage could be a bit higher given the problem of underdiagnosis and ignorance. This includes people with blood cancers or other cancers being treated with chemotherapy, and those taking medications after an organ transplant or who are taking immunosuppressive drugs for conditions including multiple sclerosis and rheumatoid arthritis," the company said.
What is Evusheld?
Evusheld is a combination of two long-acting monoclonal antibodies and is the only antibody therapy authorised in the US for COVID-19 pre-exposure prophylaxis. It is delivered as an intramuscular dose, the company said.
AstraZeneca Executive Vice President, BioPharmaceuticals R&D Mene Pangalos said, "...with Evusheld, we now have the first antibody therapy authorised in the US to prevent COVID-19 symptoms before virus exposure, while also providing long lasting protection with a single dose."
Pangalos further said, "Evusheld neutralises all previous SARs-CoV-2 variants to date, and we are working quickly to establish its efficacy against the new Omicron variant. We thank our clinical trial participants, the investigators, scientists, and government agencies and our colleagues at AstraZeneca who have all contributed to the development of Evusheld."
The company also said studies are underway to provide information on the impact of the new Omicron variant on Evusheld, which is being developed with support from the US government.
AstraZeneca said it has agreed to supply the US government with 7 lakh doses of Evusheld, while it is progressing with filings around the globe for potential emergency use authorisation or conditional approval of Evusheld in both COVID-19 prophylaxis and treatment.
While the proliferation of private labels has given an inexpensive alternative to price-conscious consumers, there is definitely a yawning gap between the demand for branded clothing and the presence of exclusive brand outlets in Indian towns. In such a scenario, retailers are rapidly expanding their store count and Internet connectivity through smartphones is expanding the reach of online retailers.
“A true representation of art meeting culture in fashion, the project has pushed designers to rediscover Merino wool and India’s heritage. They have also mirrored key qualities of wool in their designs and paid homage to India’s culture. This association will strengthen our effort to empower and promote both the wool and the handloom industry in India through local retail and weave together two cultures.”
Myntra Shopping Groups enables customers to form groups of shoppers consisting of their friends and families on the platform and shop together to avail special discounts and offers. Group members will be eligible for multiple rewards and discounts depending on the size of their shopping bags.
Global Retail Presence – Simon Carter holds the distinction of being the most successful international designer with seven standalone designer brand stores in some of the most posh locales in the UK. His much sought-after collections are retailed in some of the most exclusive department stores and independent retail outlets in 35 countries around the world including Liberty, Bloomingdales (USA), Seibu (Japan), Brown Thomas (Ireland), and David Jones (Australia).1. SIMON CARTER
Indian IT major Tata Consultancy Services (TCS) on Monday said it would transform British retail major Marks & Spencer (M&S) into a digital first business.As part of its five-year plan to transfer its business, the retailer will make best use of the digital technology to deliver more commercial opportunities
According to Manohar Samuel, President – Marketing, Birla Cellulose, “Market research conducted by Liva stated that 92 per cent women buyers choose garments made of Liva fabric over other fabrics once they have experienced the fabric. This gave us the idea of placing Liva Fashion Advisor at stores. We are confident of the high quality of Liva fabric as it is manufactured through the value chain partners accredited by the Aditya Birla Group. We want the customers to experience the fabric and Liva Fashion Advisors will help us achieve this.”
In today’s age of multi-channel retailing, Indian consumers have the luxury of choosing from a platform as per their convenience. Easy accessibility through the multiple channels has also led to a rise in the number of brands the consumer can select from according to his or her purchasing ability. While a well-travelled Indian will be familiar with international brands, the Internet and broadcasting media is contributing immensely in building consumer awareness about brands and products available not only in India but also in international markets. This has helped brands significantly in spreading their marketing campaigns to consumers in all parts of the country.1. Fashion and Consumerism
Elaborating on thetechnological advancements his brand is embracing, Beig stated, “With the world moving so fast, we have to be very tech-savvy. We will soon be introducing an entire tech-based collection. This means that technology will be an integral part of the garment we are selling.”
ASICS is the acronym for ‘Anima Sana In Corpore Sano’, meaning “A Sound Mind in a Sound Body” in Latin, encouraging the pursuit of mental and physical health and well-being. This mantra will be consistently channeled through the fully integrated sports environment brought to life in an innovative and elevated shopping experience where both the mind and body are inspired.
ASICS America Corporation, the true sport performance brand, has opend the doors to its first U.S. flagship store featuring two brands in the ASICS family – ASICS and ASICSTIGERTM.The new store on the famed Fifth Avenue in New York City is designed to represent its storied heritage and its mantra and trademark, Sound Mind, Sound Body as well as unveil a new platform for the brand to reach a wider variety of consumers
Amit Kumar, CEO Globus Stores Private Ltd. said, “Fruits of a good collaboration are always sweet and Globus store has more of generation Z buyers who will get exposure to unique khadi apparels of different flavours along with other village industry products like essential oil, soaps in their store. The 1st store opened at New Delhi has marked very encouraging sales of Rs 1,800 per sq. feet which has proved as best so far.”